Adolescents who receive two doses less than 5 months apart will require a third dose of HPV vaccine.The second dose of HPV vaccine should be given 6 to 12 months after the first dose.Two doses of HPV vaccine are recommended for most persons starting the series before their 15 th birthday.
People who are in a long-term, mutually monogamous relationship are not likely to get a new HPV infection. At any age, having a new sex partner is a risk factor for getting a new HPV infection.
Most sexually active adults have already been exposed to HPV, although not necessarily all of the HPV types targeted by vaccination. HPV vaccine works best when given before any exposure to HPV. Keep in mind that HPV vaccination prevents new HPV infections but does not treat existing HPV infections or diseases. See ACIP’s shared clinical decision-making FAQs. HPV vaccination does not need to be discussed with most adults over age 26 years. For adults ages 27 through 45 years, clinicians can consider discussing HPV vaccination with people who are most likely to benefit.HPV vaccination of people in this age range provides less benefit, for several reasons, including that more people in this age range have already been exposed to HPV. Some adults ages 27 through 45 years might decide to get the HPV vaccine based on discussion with their clinician, if they did not get adequately vaccinated when they were younger. Vaccination is not recommended for everyone older than age 26 years.HPV vaccination is given as a series of either two or three doses, depending on age at initial vaccination. ACIP also recommends vaccination for everyone through age 26 years if not adequately vaccinated when younger.HPV vaccine is recommended for routine vaccination at age 11 or 12 years.For the full text of CDC’s Advisory Committee on Immunization Practices (ACIP) recommendations, see the Human Papillomavirus (HPV) ACIP Vaccine Recommendations.
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